Diagnóstico y manejo de colitis ulcerosa grave. Una mirada actualizada

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dc.contributor.authorHernandez Rocha, Cristian
dc.contributor.authorIbanez, Patricio
dc.contributor.authorElena Molina, Maria
dc.contributor.authorKlaassen, Julieta
dc.contributor.authorValenzuela, Andrea
dc.contributor.authorCandia, Roberto
dc.contributor.authorBellolio, Felipe
dc.contributor.authorZuniga, Alvaro
dc.contributor.authorMiguieles, Rodrigo
dc.contributor.authorFrancisco Miquel, Juan
dc.contributor.authorChianale, Jose
dc.contributor.authorAlvarez Lobos, Manuel
dc.date.accessioned2024-01-10T13:50:13Z
dc.date.available2024-01-10T13:50:13Z
dc.date.issued2017
dc.description.abstractUlcerative Colitis (UC) is a chronic inflammatory disease involving the colon, with alternating periods of remission and activity. Exacerbations can be severe and associated with complications and mortality. Diagnosis of severe UC is based on clinical, biochemical and endoscopic variables. Patients with severe UC must be hospitalized. First line therapy is the use of intravenous corticoids which achieve clinical remission in most patients. However, 25% of patients will be refractory to corticoids, situation that should be evaluated at the third day of therapy. In patients without response, cytomegalovirus infection must be quickly ruled out to escalate to second line therapy with biological drugs or cyclosporine. Total colectomy must not be delayed if there is no response to second line therapy, if there is a contraindication for second line therapies or there are complications such as: megacolon, perforation or massive bleeding. An active management with quick escalation on therapy allows to decrease the prolonged exposure to corticoids, reduce colectomy rates and its perioperative complications.
dc.fechaingreso.objetodigital2024-06-26
dc.format.extent10 páginas
dc.fuente.origenWOS
dc.identifier.doi10.4067/S0034-98872017000100013
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.urihttp://dx.doi.org/10.4067/S0034-98872017000100013
dc.identifier.urihttps://doi.org/10.4067/S0034-98872017000100013
dc.identifier.wosidWOS:000395362900013
dc.information.autorucMedicina; Ibanez P;S/I;135641
dc.information.autorucMedicina; Miquel J;S/I;72216
dc.information.autorucMedicina;Alvarez M;S/I;6131
dc.information.autorucMedicina;Bellolio F;S/I;9713
dc.information.autorucMedicina;Candia R;S/I;16705
dc.information.autorucMedicina;Chianale J;S/I;99780
dc.information.autorucMedicina;Hernandez C;S/I;175117
dc.information.autorucMedicina;Klaassen J;S/I;100024
dc.information.autorucMedicina;Miguieles R;S/I;1009541
dc.information.autorucMedicina;Molina M;S/I;102077
dc.information.autorucMedicina;Valenzuela A;S/I;158199
dc.information.autorucMedicina;Zuniga A;S/I;99112
dc.issue.numero1
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final105
dc.pagina.inicio96
dc.revistaRevista Médica de Chile
dc.rightsacceso abierto
dc.subjectColitis
dc.subjectUlcerative
dc.subjectColonic Diseases
dc.subjectDrug Therapy
dc.subjectInflammatory Bowel Diseases
dc.subjectINFLAMMATORY-BOWEL-DISEASE
dc.subjectNONSTEROIDAL ANTIINFLAMMATORY DRUGS
dc.subjectCLOSTRIDIUM-DIFFICILE INFECTION
dc.subjectCYTOMEGALOVIRUS-INFECTION
dc.subjectENTERAL NUTRITION
dc.subjectSUBTOTAL COLECTOMY
dc.subjectCLINICAL-ASPECTS
dc.subjectCONTROLLED-TRIAL
dc.subjectNATURAL-HISTORY
dc.subjectRESCUE THERAPY
dc.subject.deweyMedicina y salud
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.subject.otherColon - Enfermedades
dc.subject.otherColitis ulcerosa - Diagnóstico
dc.subject.otherColitis ulcerosa - Terapia
dc.titleDiagnóstico y manejo de colitis ulcerosa grave. Una mirada actualizada
dc.title.alternativeManagement of severe ulcerative colitis. An up-to-date
dc.typeartículo
dc.volumen145
sipa.codpersvinculados135641
sipa.codpersvinculados72216
sipa.codpersvinculados6131
sipa.codpersvinculados9713
sipa.codpersvinculados16705
sipa.codpersvinculados99780
sipa.codpersvinculados175117
sipa.codpersvinculados100024
sipa.codpersvinculados1009541
sipa.codpersvinculados102077
sipa.codpersvinculados158199
sipa.codpersvinculados99112
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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