Clinical characteristics, systemic complications, and in-hospital outcomes for patients with COVID-19 in Latin America. LIVEN-Covid-19 study: A prospective, multicenter, multinational, cohort study

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dc.contributor.authorReyes, Luis F.
dc.contributor.authorBastidas, Alirio
dc.contributor.authorNarvaez, Paula O.
dc.contributor.authorParra-Tanoux, Daniela
dc.contributor.authorFuentes, Yuli, V
dc.contributor.authorSerrano-Mayorga, Cristian C.
dc.contributor.authorOrtiz, Valentina
dc.contributor.authorCaceres, Eder L.
dc.contributor.authorOspina-Tascon, Gustavo
dc.contributor.authorDiaz, Ana M.
dc.contributor.authorJibaja, Manuel
dc.contributor.authorVera, Magdalena
dc.contributor.authorSilva, Edwin
dc.contributor.authorGorordo-Delsol, Luis Antonio
dc.contributor.authorMaraschin, Francesca
dc.contributor.authorVaron-Vega, Fabio
dc.contributor.authorBuitrago, Ricardo
dc.contributor.authorPoveda, Marcela
dc.contributor.authorSaucedo, Lina M.
dc.contributor.authorEstenssoro, Elisa
dc.contributor.authorOrtiz, Guillermo
dc.contributor.authorNin, Nicolas
dc.contributor.authorCalderon, Luis E.
dc.contributor.authorMontano, Gina S.
dc.contributor.authorChaar, Aldair J.
dc.contributor.authorGarcia, Fernanda
dc.contributor.authorRamirez, Vanessa
dc.contributor.authorPicoita, Fabricio
dc.contributor.authorPelaez, Cristian
dc.contributor.authorUnigarro, Luis
dc.contributor.authorFriedman, Gilberto
dc.contributor.authorCucunubo, Laura
dc.contributor.authorBruhn, Alejandro
dc.contributor.authorHernandez, Glenn
dc.contributor.authorMartin-Loeches, Ignacio
dc.date.accessioned2024-01-10T13:10:35Z
dc.date.available2024-01-10T13:10:35Z
dc.date.issued2022
dc.description.abstractPurpose
dc.description.abstractThe COVID-19 pandemic has spread worldwide, and almost 396 million people have been infected around the globe. Latin American countries have been deeply affected, and there is a lack of data in this regard. This study aims to identify the clinical characteristics, in-hospital outcomes, and factors associated with ICU admission due to COVID-19. Furthermore, to describe the functional status of patients at hospital discharge after the acute episode of COVID-19.
dc.description.abstractMaterial and methods
dc.description.abstractThis was a prospective, multicenter, multinational observational cohort study of subjects admitted to 22 hospitals within Latin America. Data were collected prospectively. Descriptive statistics were used to characterize patients, and multivariate regression was carried out to identify factors associated with severe COVID-19.
dc.description.abstractResults
dc.description.abstractA total of 3008 patients were included in the study. A total of 64.3% of patients had severe COVID-19 and were admitted to the ICU. Patients admitted to the ICU had a higher mean (SD) 4C score (10 [3] vs. 7 [3)], p<0.001). The risk factors independently associated with progression to ICU admission were age, shortness of breath, and obesity. In-hospital mortality was 24.1%, whereas the ICU mortality rate was 35.1%. Most patients had equal self-care ability at discharge 43.8%; however, ICU patients had worse self-care ability at hospital discharge (25.7% [497/1934] vs. 3.7% [40/1074], p<0.001).
dc.description.abstractConclusions
dc.description.abstractThis study confirms that patients with SARS CoV-2 in the Latin American population had a lower mortality rate than previously reported. Systemic complications are frequent in patients admitted to the ICU due to COVID-19, as previously described in high-income countries.
dc.fuente.origenWOS
dc.identifier.doi10.1371/journal.pone.0265529
dc.identifier.issn1932-6203
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0265529
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77890
dc.identifier.wosidWOS:000799828800037
dc.information.autorucFacultad de Medicina; Vera Alarcon, Maria Magdalena; S/I; 226652
dc.issue.numero3
dc.language.isoen
dc.nota.accesoSin adjunto
dc.publisherPUBLIC LIBRARY SCIENCE
dc.rightsregistro bibliográfico
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleClinical characteristics, systemic complications, and in-hospital outcomes for patients with COVID-19 in Latin America. LIVEN-Covid-19 study: A prospective, multicenter, multinational, cohort study
dc.typeartículo
dc.volumen17
sipa.codpersvinculados226652
sipa.indexWOS
sipa.trazabilidadCarga SIPA;09-01-2024
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