Diagnostic performance of image navigated coronary CMR angiography in patients with coronary artery disease

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dc.contributor.authorBotnar, René Michael
dc.contributor.authorHenningsson, Markus.
dc.contributor.authorShome, Joy.
dc.contributor.authorBratis, Konstantinos.
dc.contributor.authorVieira, Miguel Silva.
dc.contributor.authorNagel, Eike.
dc.date.accessioned2019-10-17T14:31:57Z
dc.date.available2019-10-17T14:31:57Z
dc.date.issued2017
dc.date.updated2019-10-14T19:00:31Z
dc.description.abstractAbstract Background The use of coronary MR angiography (CMRA) in patients with coronary artery disease (CAD) remains limited due to the long scan times, unpredictable and often non-diagnostic image quality secondary to respiratory motion artifacts. The purpose of this study was to evaluate CMRA with image-based respiratory navigation (iNAV CMRA) and compare it to gold standard invasive x-ray coronary angiography in patients with CAD. Methods Consecutive patients referred for CMR assessment were included to undergo iNAV CMRA on a 1.5 T scanner. Coronary vessel sharpness and a visual score were assigned to the coronary arteries. A diagnostic reading was performed on the iNAV CMRA data, where a lumen narrowing >50% was considered diseased. This was compared to invasive x-ray findings. Results Image-navigated CMRA was performed in 31 patients (77% male, 56 ± 14 years). The iNAV CMRA scan time was 7 min:21 s ± 0 min:28 s. Out of a possible 279 coronary segments, 26 segments were excluded from analysis due to stents or diameter less than 1.5 mm, resulting in a total of 253 coronary segments. Diagnostic image quality was obtained for 98% of proximal coronary segments, 94% of middle segments, and 91% of distal coronary segments. The sensitivity and specificity was 86% and 83% per patient, 80% and 92% per vessel and 73% and 95% per segment. Conclusion In this study, iNAV CMRA offered a very good diagnostic performance when compared against invasive x-ray angiography. Due to the short and predictable scan time it can add clinical value as a part of a comprehensive CAD assessment protocol.
dc.fuente.origenBiomed Central
dc.identifier.citationJournal of Cardiovascular Magnetic Resonance. 2017 Sep 11;19(1):68
dc.identifier.doi10.1186/s12968-017-0381-3
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/26707
dc.identifier.wosidWOS:000410237300001
dc.issue.numeroNo. 68
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final8
dc.pagina.inicio1
dc.revistaJournal of Cardiovascular Magnetic Resonancees_ES
dc.rightsacceso abierto
dc.rights.holderThe Author(s).
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.subject.otherAngiografía coronariaes_ES
dc.subject.otherEnfermedad coronariaes_ES
dc.subject.otherCardiopatía coronariaes_ES
dc.titleDiagnostic performance of image navigated coronary CMR angiography in patients with coronary artery diseasees_ES
dc.typeartículo
dc.volumenVol. 19
sipa.codpersvinculados1015313
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