<i>N</i>-Arylation of 3-Formylquinolin-2(1<i>H</i>)-ones Using Copper(II)-Catalyzed Chan-Lam Coupling

Simple item page
dc.contributor.authorValencia, Jhesua
dc.contributor.authorSanchez-Velasco, Oriel A.
dc.contributor.authorSaavedra-Olavarria, Jorge
dc.contributor.authorHermosilla-Ibanez, Patricio
dc.contributor.authorPerez, Edwin G.
dc.contributor.authorInsuasty, Daniel
dc.date.accessioned2025-01-20T21:01:13Z
dc.date.available2025-01-20T21:01:13Z
dc.date.issued2022
dc.description.abstract3-formyl-2-quinolones have attracted the scientific community's attention because they are used as versatile building blocks in the synthesis of more complex compounds showing different and attractive biological activities. Using copper-catalyzed Chan-Lam coupling, we synthesized 32 new N-aryl-3-formyl-2-quinolone derivatives at 80 degrees C, in air and using inexpensive phenylboronic acids as arylating agents. 3-formyl-2-quinolones and substituted 3-formyl-2-quinolones can act as substrates, and among the products, the p-methyl derivative 9a was used as a substrate to obtain different derivatives such as alcohol, amine, nitrile, and chalcone.
dc.fuente.origenWOS
dc.identifier.doi10.3390/molecules27238345
dc.identifier.eissn1420-3049
dc.identifier.urihttps://doi.org/10.3390/molecules27238345
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92835
dc.identifier.wosidWOS:000897348200001
dc.issue.numero23
dc.language.isoen
dc.revistaMolecules
dc.rightsacceso restringido
dc.subjectChan-Lam coupling
dc.subjectcopper(II)
dc.subjectN-arylation
dc.subject3-formylquinolones
dc.title<i>N</i>-Arylation of 3-Formylquinolin-2(1<i>H</i>)-ones Using Copper(II)-Catalyzed Chan-Lam Coupling
dc.typeartículo
dc.volumen27
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas